Basic Radiobiology of Rpt
Radiopharmaceuticals, Theranostics, and Nuclear Medicine
Invited Program · Radiopharmaceuticals, Theranostics, and Nuclear Medicine
Author profile
Remco Bastiaannet, PhD
Mallinckrodt Institute of Radiology
Quantitative Autoradiography-Based Stochastic Microscale Dosimetry for α-Emitter Radiopharmaceutical Therapy
Mean absorbed dose is commonly used to interpret radiopharmaceutical therapy outcomes. For α-emitter radiopharmaceutical therapy (αRPT), however, energy deposition is stochastic at the cellular scale, while tissue-level Monte Carlo-based microdosimetry is com...
Proffered Program · Radiopharmaceuticals, Theranostics, and Nuclear Medicine
From Microscopic Energy Deposition to Biological Response: Modeling Needs in Radiopharmaceutical Therapy
IM/TH- Radiopharmaceutical Therapy
Invited Program · IM/TH- Radiopharmaceutical Therapy
BEST IN PHYSICS (RADIOPHARMACEUTICALS): Quantitative Decay-Chain-Resolved Autoradiography Enables Microscale Assessment of ²²⁵Ac Daughter Redistribution In Tissue
Redistribution of radioactive daughters following ²²⁵Ac decay is a major dose-limiting uncertainty in α-emitter radiopharmaceutical therapy (αRPT). Free daughter species may diffuse from their site of origin, yet their microscale fate within tissue remains po...
Proffered Program · Radiopharmaceuticals, Theranostics, and Nuclear Medicine