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Author profile
Jie Fu, PhD, MS
Department of Radiation Oncology, University of Washington and Fred Hutchinson Cancer Center
Advances In Intensity Modulated Neutron Therapy (IMNT): Improvement In Plan Quality and Reduction In Treatment Time through Beam Angle Optimization (BAO) and Field Co-Optimization
High linear energy transfer (LET) IMNT faces practical delivery constraints: low output rates (~55 MU/min), manual gantry and couch rotations (~3-5 min/field), and mandatory wait times (~1-2 min/field) for neutron activation concerns. Our standard-of-care (SO...
Poster Program · Therapy Physics
Uncertainty-Aware Multimodal Biomarker-Guided Treatment Response Prediction: Integrating FDG PET, T-cell Repertoire, and Inflammatory Cytokines with Conformal Uncertainty Quantification
Uncertainty-aware multimodal biomarker-guided treatment response prediction in metastatic NSCLC remains a critical unmet need to support robust therapy selection and adaptation over time. We developed a multimodal framework integrating FDG-PET, T-cell recepto...
Poster Program · Therapy Physics
Implementation of Web-Based QA Management Platform at Multi-Clinic, Multi-Vendor Institution.
A web-based quality assurance (QA) management platform can reduce clinic hardware and software needs while streamlining QA workflows through improved accessibility, trend tracking, and automated failure notifications. This study reports on the implementation...
Poster Program · Therapy Physics
Uncertainty-Aware Multiscale Patient- and Voxel-Level Treatment Response Forecasting for Personalized Radiotherapy Using Conformal Prediction In Advanced Non-Small Cell Lung Cancer (NSCLC)
Multiscale treatment response prediction in advanced NSCLC enables spatially informed dose painting, yet prediction point estimates alone do not convey the uncertainty required for adaptive therapy decision support. We developed a multiscale conformal predict...
Poster Program · Therapy Physics
Voxel-Wise Characterization of Post-Radiotherapy Liver Function Changes Using Longitudinal Sulfur Colloid SPECT/CT
Patients receiving radiotherapy (RT) for liver cancer have limited liver function reserves, which increases risk of radiation-induced liver injury, but tools to evaluate functional response post-RT are lacking. We modeled liver function changes on 99mTc sulfu...
Proffered Program · Therapy Physics