Ultra-high dose rate (UHDR) beams (40Gy/s) compromise the accuracy of conventional reference ion chambers (ICs) due to saturation effects. The Exradin A30 is an ultra-thin parallel-plate IC featuring a 0.3 mm nominal electrode spacing to enhance the charge co...
Author profile
Emil Schueler
MDACC
The beam output of linacs producing ultra-high dose rates for FLASH radiotherapy (FLASH linacs) can exhibit significant and sometimes unpredictable variations in response to beam parameter adjustments, differing even among identical models. This study aims to...
Ionization chambers represent the gold standard for clinical dosimetry; however, they suffer from severe ion recombination losses at the ultra-high dose rates (UHDR) characteristic of FLASH radiotherapy. This study evaluates the new commercial Exradin A30 par...
To evaluate the dosimetric performance and surface conformality of a commercially available brass mesh bolus (BMB) compared with 3 mm Superflab (SF) in clinically realistic scenarios where air gaps are expected, such as in patients with tissue expanders.
Therapy Physics
To establish a preclinical x-ray platform for delivering broad-beam (BB) and spatially-fractionated radiotherapy (SFRT) at conventional (CONV) and ultra-high dose rates (UHDR), and to determine the capacity for SFRT to maintain tumor control at doses elicitin...
FLASH radiotherapy (FLASH‑RT) employs ultra‑high dose rates (UHDR) that preferentially spare normal tissues relative to conventional dose‑rate radiotherapy (CONV‑RT) while maintaining tumor control, this is known as the FLASH effect. A proposed mechanistic ex...
To design and validate a phantom capable of remote temporal and point dose rate assessment for electron and proton FLASH beams, with integrated spatial information to enable full end to end verification.