Author profile
University of Nebraska Medical Center
To mechanistically define the beam parameter space required for FLASH radioprotection, moving beyond Mean Dose Rate (MDR) to identify critical constraints in pulse structure (dose-per-pulse and frequency).
To develop a mechanistic extension of the classical Lethal and Potentially Lethal (LPL) model that explains oxygen-mediated ultra-high dose rate (FLASH) sparing without prescribing dose-rate–dependent radiosensitivity.
MC simulations were used to accurately determine the water-equivalent thickness (WET) of the buildup housing, the effective point of measurement (EPOM), and the proton- and chamber-specific factor fQ, the MC-derived component of the beam quality correction fa...
This work aims to develop a physics-aware deep learning framework for radiotherapy dose prediction that improves accuracy and clinical efficiency. The proposed Physics-Aware Multimodal UNet (PhysMM-UNet) integrates CT images, fluence maps, organ masks, and mu...
Ultrasound-guided high-dose-rate (UGHDR) brachytherapy for prostate cancer depends on real-time transrectal ultrasound (TRUS) imaging for catheter guidance. However, the limited ability of TRUS to depict critical bony anatomy, such as the pubic arch, poses ch...
To quantify the dosimetric consequences of physiology-composed abdominal motion on pancreatic cancer SBRT.