Deshan Yang, PhD

Glioblastoma has a low median survival of 3cm from the tumor, where deformation is minimal. Vessels 80% of patients. Future work will incorporate this pathway into a full front-to-end deformable registration approach to precisely determine the origin of recur...

To propose a federated learning (FL) framework incorporating a novel deep ensemble strategy for multi-institutional brain metastasis (BM) segmentation, improving performance in limited local datasets while preserving privacy by avoiding large-scale data trans...

Effective radiotherapy for upper abdominal tumors requires dose escalation but is limited by respiratory motion and the low gastrointestinal radiation tolerance. Current clinical motion management on conventional Linacs relies on simple external surrogates th...

Low grade diffuse gliomas are slow-growing tumors that must be monitored longitudinally to detect progression to more aggressive higher-grade disease. However, the slow growth of these tumors can make it difficult for radiologists to appreciate subtle tumor c...

To develop a multi-parametric MRI (mp-MRI) radiomics framework for predicting post-resection glioblastoma (GBM) survival by integrating conventional MR modalities with a quantum mechanics–inspired imaging representation.

To develop and evaluate a federated learning (FL) framework for brain metastasis (BM) segmentation that integrates an uncertainty score into a novel FL objective, improving segmentation robustness and potentially performance when training on limited-size data...

To study the cardiac and respiratory heart motion together. Cardiorespiratory motion management is a significant topic in stereotactic arrhythmia radiotherapy (STAR). Cardiorespiratory motion consists of the heart beating and respiration. Commonly studied sep...

It was critical yet impossible to quantitatively assess the impact of patient-specific cardiorespiratory motion on dose plans for stereotactic arrhythmia radioablation (STAR) treatments. To fill the gap, a fast algorithm, SPM (spatial probability map), was de...

Radiotherapy for upper abdominal cancers is limited by respiratory motion and the low radiation tolerance, restricting safe dose escalation. Conventional linear accelerators rely on kV X-ray and CBCT imaging but lack real-time internal motion tracking capabil...

Managing cardiac and respiratory motion is critical for stereotactic arrhythmia radiotherapy (STAR), thoracic, and breast treatments. Breath-hold cardiac 4DCT (c4DCT) is commonly required for assessing cardiac motion, while respiratory 4DCT (r4DCT) is used fo...

Therapy Physics