To apply a proton procedure of optimizing spot weight and Ridge Filter (RF) to single-energy carbon pencil beam and evaluate it in a water phantom with a square-shape target in the center (prescription dose 50 Gy).
Author profile
Radhe Mohan, PhD
Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
To develop an optimization procedure of spot weight and ridge filter (RF) dimension for single-energy proton pencil beam and apply it to a water phantom with a square-shape target in the center (prescription dose 50 Gy).
Current clinical toxicity models for predicting radiation-induced pneumonitis are limited by lack of functional information; furthermore, current practice assumes a relative biological effectiveness (RBE) of 1.1 for proton therapy patients. We hypothesize tha...
Enhanced relative biological effectiveness (RBE) Carbon Ion Radiotherapy (CIRT) may provide a promising tool to eradicate therapy-resistant tumors such as pancreatic ductal adenocarcinoma (PDAC). Novel KRASG12D inhibitors have demonstrated CD8+ T-cell depende...
FLASH radiotherapy (FLASH‑RT) employs ultra‑high dose rates (UHDR) that preferentially spare normal tissues relative to conventional dose‑rate radiotherapy (CONV‑RT) while maintaining tumor control, this is known as the FLASH effect. A proposed mechanistic ex...