Author profile
Medical Physics Program College of Medicine, University of Florida
To develop a slice-specific CT organ dose library using Monte Carlo radiation transport simulations on a set of newborn, infant, and toddler (NIT) computational phantoms containing newly developed age-specific skeletal tissue models. This dose library forms t...
To develop tetrahedral mesh-based tissue models at the macro and micro-scale of the International Commission on Radiological Protection (ICRP) adult female mesh-type reference computational phantom (MRCP) breast inclusive of tissue-specific vasculature models...
To develop tetrahedral mesh-type phantoms of the female and male beagle dog and perform Monte Carlo (MC) radiation transport simulations to compute specific absorbed fractions (SAFs) for monoenergetic photons, electrons and alpha particles. These canine phant...
Current Y-90 radioembolization (RE) standard dosimetry assumes homogeneous microsphere distribution, ignoring patient-specific vasculature heterogeneity. We developed a framework to reproduce and augment patient-specific hepatic vascular models from cone-beam...
In the rapidly developing field of radiopharmaceuticals, the skeleton poses a uniquely daunting challenge to any effort to safely employ these powerful tools. The skeleton’s wide distribution throughout the body as well as its variability make dose difficult...
The skeleton is of particular concern in radiation dosimetry, because it contains key target tissues for radiogenic cancers, including red bone marrow (RBM), associated with leukemia risk. However, skeletal dosimetry remains challenging due to the complex mic...
In preclinical studies, animal models are widely used to estimate absorbed doses following the administration of radiopharmaceuticals. Mice are the most commonly used models; however, their small body size can lead to biased dose estimates when translating mo...