To quantify the effect of interfractional anatomic variation on dose-averaged linear energy transfer (LETd) in head-and-neck intensity-modulated proton therapy (IMPT), and to determine whether daily adaptive proton therapy (APT) further alters LETd compared w...
Author profile
Mislav Bobić, PhD
Massachusetts General Hospital and Harvard Medical School
Impact of Online Adaptive Proton Therapy on Linear Energy Transfer In Head-and-Neck Cancer Under Daily Anatomic Variation
Poster Program · Therapy Physics
Patient-Specific Liver Vasculature Phantoms for Y-90 Radioembolization Dosimetry
Current Y-90 radioembolization (RE) standard dosimetry assumes homogeneous microsphere distribution, ignoring patient-specific vasculature heterogeneity. We developed a framework to reproduce and augment patient-specific hepatic vascular models from cone-beam...
Poster Program · Radiopharmaceuticals, Theranostics, and Nuclear Medicine
Dynamic Prediction of Radiation-Induced Arrhythmia Using Landmark Modeling with Longitudinal Heart Rate and Cardiac Substructure Dosimetry
Radiation therapy–associated cardiac arrhythmia is a clinically significant complication of thoracic RT, with important consequences for long-term cardiovascular health and treatment outcomes. Although arrhythmia risk evolves over time and is linked to cardia...
Proffered Program · Therapy Physics