Ultra-high dose rate (UHDR) beams (40Gy/s) compromise the accuracy of conventional reference ion chambers (ICs) due to saturation effects. The Exradin A30 is an ultra-thin parallel-plate IC featuring a 0.3 mm nominal electrode spacing to enhance the charge co...
Author profile
Larry A. DeWerd, PhD
Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison
To experimentally determine the effective point of measurement (EPOM) shift of an Exradin A1SL ion chamber in kilovoltage x-ray beams (40-250 kVp) using water tank measurements.
To quantify dose delivered from a scanning microbeam x-ray irradiator using partial-volume techniques with thermoluminescent dosimeters (TLD-100) chips and to improve dosimetry in systems with small fields.
Development of next-generation neutron capture therapy (NCT) agents demands rigorous preclinical testing to verify targeting efficacy, safety, and therapeutic gain under clinically relevant irradiation conditions. This work proposes a preclinical, accelerator...
The Liberty Vision Y-90 ophthalmic applicator (LV-90) is an FDA approved HDR source for episcleral brachytherapy to treat ocular tumors and benign growths. It is an attractive option for patients because it does not require episcleral sutures, muscle relocati...
With advances in Targeted Alpha Therapy (TAT) preclinical and clinical research, the importance for accurate and traceable dosimetry with sub-organ resolution becomes critical. Current limitations in verifying imaging resolution and activity quantification hi...
Accurate absorbed dose determination for alpha emitting sources remains challenging due to short particle ranges and sensitivity to source geometry. This work presents a practical framework for direct absorbed dose to water measurements from a plated 241Am so...
Absolute measurements offer the highest metrological quality. Known-volume ionization chambers are absolute dosimeters that determine air-kerma for photon energies above 300 keV, where free-air chambers are impractical. The precise volume determination of cav...