In Vivo Study of Total-Body Kinetics of Ac-225 and Its Daughters in Mouse Using a CZT-Based Small Animal SPECT-CT System
We present a small-animal SPECT-CT system based on CZT imaging spectrometers and a rapidly switchable dual-FOV apertures. The system supports both total-body imaging and focused, high-resolution imaging. These capabilities address a key need in preclinical ra...
Poster Program · Radiopharmaceuticals, Theranostics, and Nuclear Medicine
Quantitative Evaluation of Reconstruction Methods for 180° Vs. 360° Acquisition Protocols In 99mTc-Sestamibi SPECT of Renal Tumors
Quantitative 99mTc-sestamibi SPECT/CT is routinely used to distinguish benign kidney tumors from renal cell carcinoma. Standard clinical acquisitions typically use 360° orbits. However, a 180° posterior orbit can reduce scan time and patient discomfort. This...
Poster Program · Diagnostic and Interventional Radiology Physics
Kidney, Blood, and Bone Marrow Dosimetry of 225ac-Hu3F8 Targeted Alpha-Emitter Therapy In a Canine Model
αRPT is a promising treatment modality that is largely impervious to the mechanisms of resistance associated with chemotherapy, conventional radiotherapy, targeted (pathway-inhibition) therapies, and immunotherapy. Osteosarcoma (OS), which frequently expresse...
Proffered Program · Radiopharmaceuticals, Theranostics, and Nuclear Medicine
