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Zachary Ells
Ludwig Maximilans University
Gastrointestinal Dosimetry of 177lu-PSMA-617 Radiopharmaceutical Therapy In Metastatic Prostate Cancer Patients: Results from a Single-Center Retrospective Study
Gastrointestinal (GI) adverse events following 177Lu-PSMA radiopharmaceutical therapy (RPT) occur frequently, including nausea, vomiting, constipation, and diarrhea (occurring in 19-35% of patients). Despite the frequent occurrence of GI-related toxicities, t...
Proffered Program · Radiopharmaceuticals, Theranostics, and Nuclear Medicine
Effects of Increased Injected Activities Exceeding 9.0 Gbq [177lu]Lu-PSMA-I&t on Absorbed Doses to Lesions and Kidneys
Administration activities of 177Lu-PSMA were chosen cautiously in the treatment of advanced prostate cancer to refrain from inducing organ toxicity. The primary aim here was to investigate the association of increased injected activities and the respective ab...
Proffered Program · Therapy Physics
Impact of Bone Marrow Segmentation on Dose Estimates In High‑ Vs Low‑ Disease Burden Patients Treated with 177lu‑PSMA‑617
Bone marrow (BM) is an organ-at-risk for 177Lu-PSMA radiopharmaceutical therapy, but estimating the absorbed dose (AD) is challenged by the segmentation of disseminated BM. In this work, we evaluated the impact of two segmentation approaches on AD estimates i...
Proffered Program · Radiopharmaceuticals, Theranostics, and Nuclear Medicine
BLUE RIBBON POSTER RADIOPHARMACEUTICALS: Comparing Absorbed Dose Variability In ¹⁷⁷Lu‑PSMA Therapy across Calculation Methods and Commercial Software
Dosimetry software programs use different computational approaches which may lead to clinically relevant differences in reported absorbed doses (AD). This study aims to evaluate the impact of software methodology on AD calculations.
Poster Program · Radiopharmaceuticals, Theranostics, and Nuclear Medicine