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Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University
This session will present a structured, educational overview of how to perform patient-specific dosimetry in radiopharmaceutical therapy, using AAPM TG-381 as a reference framework. The first part will walk through generalizable dosimetry workflows—from imagi...
Quantitative image-based dosimetry for radiopharmaceutical therapy (RPT) increasingly relies on large, multi-organ mechanistic models of physiologically based pharmacokinetics (PBPK). While PBPK models often fit clinical data well, the extent to which their i...
In prostate-specific membrane antigen (PSMA)-targeted radiopharmaceutical therapy for metastatic castration-resistant prostate cancer, salivary glands often receive unintended high absorbed doses and are considered dose-limiting organs. For radiopharmaceutica...