Author profile
University of Iowa Health Care
This study aimed to assess three different planning approaches for treating central lung SBRT tumors using GPU Acceleration for optimization and GPUMCD for dose calculation in the Elekta One Planning treatment planning system (v6.2.3, EOP).
Dynamic collimation is emerging as a next-generation energy-specific collimating technology that can drastically improve the lateral and distal conformity of Pencil Beam Scanning (PBS) proton therapy. Current treatment delivery approaches rely on static step-...
GPUMCD, a GPU-accelerated Monte Carlo dose calculation algorithm, was recently released for clinical implementation in the Elekta One Treatment Planning System (v6.2.3, EOP) for c-arm Elekta linear accelerators (linac). The purpose of this work was to validat...
To experimentally quantify the mechanical delivery errors of a pre-clinical Dynamical Collimation System (DCS) prototype for intensity modulated proton therapy (IMPT) and evaluate the dosimetric impact of these errors to the target coverage and organ sparing.
Hyperpolarized Xenon imaging is a recent FDA-approved MRI technique that can measure physiological changes in ventilation, membrane uptake, and red blood cell transfer of gas throughout the lung. The scope of this work is to demonstrate the feasibility of int...
Dose-optimized proton pencil beam scanning (PBS) treatments that are collimated using the Dynamic Collimation System (DCS) have greater dosimetric sparing of healthy tissue compared to uncollimated treatment plans, but differences in linear energy transfer (L...