Bas W. Raaymakers, PhD

MR-linacs enable online adaptive radiotherapy, which increases dose conformality and thus potentially improves therapeutic ratios. A recurring drawback with respect to C-arm linacs is the lack of VMAT leading to decreased efficiency. Recently, it was demonstr...

Volumetric-modulated arc therapy (VMAT) plan optimization remains a challenging problem due to its non-convex character and the large dimensionality of the solution space. Commonly, the problem is split in three steps: 1) ideal fluence optimization 2) arc seq...

This study investigates the feasibility of VMAT treatments on the MR-Linac by comparing planned and measured quality and deliverability of investigational VMAT plans with existing clinical IMRT plans to determine whether VMAT can maintain clinically acceptabl...

Computed tomography ventilation imaging (CTVI) allows generating ventilation maps from CT data. CTVI provides spatially resolved information on regional lung function that can support functional avoidance and adaptive treatment strategies, but its current rel...

Intensity modulated radiotherapy (IMRT) is the current standard delivery technique on MR-linacs. IMRT deliveries cycle between radiating and moving segments, each starting with loading the segment. More complex plans usually contain more radiating segments, i...

Effectiveness of EBRT depends highly on target coverage, which is challenged by inter- and intra-fraction anatomical motion. MR-guided radiotherapy (MRgRT) reduces the need for inter-fraction planning margins, by daily adaptive planning, for which daily recon...