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Polytechnique Montréal
To evaluate the relationship between quantitative MRI relaxation parameters (T1, T2, T*2, and T'2) at 3T and hypoxia level in three-dimensional (3D) cancer cell spheroids under controlled in-vitro conditions, using western blot measurements as biological grou...
FLASH radiotherapy, defined by ultra-high dose rates (UHDR; >40 Gy/s), can reduce normal-tissue toxicity while maintaining tumor control, yet reported FLASH effects show substantial variability across experimental and preclinical studies. Dielectric materials...
A microfluidic lab-on-a-chip integrating an I-125 brachytherapy seed has recently been developed for radiobiological irradiation of spheroids. This study investigates a novel seed-through-film geometry suitable to validate the dosimetry of this device in the...