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New York Proton Center
Traditional patient-specific QA in proton therapy requires detector-based measurements that consume beam time and delay workflow. This study presents a calibration-based machine log analysis system enabling automated, measurement-free verification of delivere...
To investigate the role of interplay effects between respiratory motion and proton scanning beam interactions on free-breathing proton lattice radiotherapy (PLT) plans relative to dose distributions from static calculations.
Hypofractionated proton therapy for pancreatic cancer is limited by the proximity of radiosensitive abdominal organs. Single-energy Bragg peak (SEBP) proton delivery enables ultra-high dose-rate (UHDR) irradiation and may facilitate FLASH compatible treatment...
While 30% of lung cancer patients cannot tolerate breath-hold, free-breathing(FB) proton pencil-beam-scanning(PBS) deliveries compromise target coverage from the interplay effects of large motion. This study presents a novel FB-gated spirometer-based respirat...
Ultra-high-dose-rate (UHDR) proton irradiation may spare normal tissue (FLASH effect), but PBS proton dose rate is limited by machine constraints (minimum MU/spot and dwell time). Intra-field interruptions can leave sub-threshold MU for remaining delivery, de...
To systematically evaluate if optimized spot-delivery patterns in pencil-beam scanning can reach FLASH-compatible dose rates (>40Gy/s) at clinically relevant fractions of 4Gy and to identify key machine and planning parameters for whole-brain irradiation (WBI...