Kinase-substrate interactions are inherently directional: kinases phosphorylate substrates, not vice versa, yet most network-based methods ignore this asymmetry, potentially discarding predictive signal.1 We investigated whether respecting biological directio...
Author profile
Hui Lin, PhD
Department of Radiation Oncology, University of California San Francisco
Leveraging AI and Directional Phosphorylation Network for Drug Response Prediction In BRAF-Mutant Colorectal Cancer
Poster Program · Therapy Physics
Staged Alignment of Decoder Large Language Models for Oncology Tasks Via Radiology-Pathology Note Pairing
Decoder large language models (LLMs) like ChatGPT and Claude show excellent text understanding in general domains but remain under-aligned to oncology-specific clinical context. This study aims to design and validate an alignment pipeline for decoder-based LL...
Poster Program · Diagnostic and Interventional Radiology Physics
Can Vlms Read Glioma Mris? Building a Diagnostic Benchmark Using Public Multi-Parametric MRI and EHR Dataset
The rapid advancement of Vision-Language Models (VLMs) offers transformative potential for automated radiology; however, their ability to interpret 3D brain tumor imaging remains underexplored. This study introduces a rigorous benchmark to evaluate the diagno...
Proffered Program · Diagnostic and Interventional Radiology Physics