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CHUM
Diffusing alpha-emitters Radiation Therapy (Alpha DaRT) requires accurate placement of radioactive sources to ensure full coverage of the Gross Tumor Volume (GTV) while minimizing the required total number and length of implanted sources. We proposed a 3D clo...
To achieve accurate dosimetric modeling of Alpha DaRT sources by accounting for the spatial superposition of dose contributions from multiple implanted sources arranged in a regular lattice geometry.
Calculation of the equivalent dose in Diffusing alpha-emitters Radiation Therapy (Alpha DaRT) depends strongly on the spatial dose distribution and the radiobiological impact of emitted alpha particles [1-3]. Current practice in clinical treatment planning sy...
This study aims to evaluate the effective RBE of recoiled nuclei and their contribution to equivalent dose estimation in Alpha DaRT, whose radiobiological impact remains poorly characterized.