Murat Surucu, PhD

To evaluate the ability of a RefleXion X2 system with extended PET-FOV with a developmental Anchor Point Tracking algorithm to autonomously follow PET-avid target and deliver dose, accounting for large sudden target displacements.

Upright radiotherapy offers physiological and dosimetric advantages. Mevion S250-FIT, world’s first clinical ultra-compact synchrocyclotron-based upright proton therapy system, incorporates a novel upright CT for treatment planning and image guidance. This st...

The RefleXion X1 system requires activity concentration (AC) >5 kBq/mL for successful biology-guided radiotherapy (BgRT). We evaluated whether the extended field-of-view (FOV) PET detector in a can lower this AC threshold and expand treatment eligibility.

Configuring clinical linear accelerators (LINACs) for ultra-high dose rate (UHDR) electron experiments typically requires invasive hardware modification or manufacturer intervention, limiting accessibility. We developed an independent, non-invasive, software-...

To assess the effectiveness of a developmental anchor point tracking algorithm with PET deblurring in targeting tumors on the RefleXion X2 platform.

The Mevion S250-FIT is the world’s first ultra-compact proton therapy system designed with a form factor compatible with existing LINAC vaults. This raises questions regarding radiation shielding adequacy and electromagnetic compatibility with adjacent radiot...

With improvements in patient outcomes, re-irradiation is increasingly pursued and is becoming a common occurrence in the clinic. Safe planning requires accurate characterization of cumulative organ-at-risk (OAR) exposure across treatment courses that may diff...

Commissioning and performance validation of the world’s first ultra-compact upright proton therapy system and establish benchmarks for this novel treatment delivery paradigm.

To examine the dose conformity during planning and delivery for complex C-shaped targets in an investigational RefleXion X2 platform under static and motion conditions.

To evaluate the robustness of the developmental X2 Anchor Point Tracking algorithm to changes in breathing patterns between SCINTIX-modeling PET (for planning) and biology-guided radiation therapy (BgRT) treatment.