Author profile
UT Southwestern Medical Center
Direct-to-Unit (simulation-omitted) radiotherapy enables treatment planning directly from diagnostic imaging, eliminating CT simulation and supporting same-day treatment for time-sensitive cases. These workflows rely on adaptive radiotherapy (ART) platforms t...
Motion management plays a critical role in radiation therapy for thoracic and abdominal tumors, where respiratory motion can significantly compromise treatment precision. Among available motion-mitigation techniques, respiratory gating offers distinct advanta...
Cone-beam CT (CBCT) acquired on the linear accelerator is being increasingly used beyond image guidance to support simulation and treatment planning workflows. This work reports the clinical implementation, challenges, and solutions associated with CBCT-based...
Combination radiopharmaceutical therapy (RPT) and external beam radiation therapy (EBRT) is an underexplored strategy that may improve outcomes over either modality alone; however, practical implementation requires a clear understanding of dosimetry and radia...
Positron Emission Tomography/Computed Tomography (PET/CT) plays a pivotal role in radiation therapy, particularly in tumor delineation, response assessment, and adaptive therapy planning. However, the reliability of PET/CT depends on key system performance an...
CBCT-based online adaptive radiotherapy (CBCT-oART) enables daily plan adaptation but is sensitive to intra-fraction motion during extended adaptive workflows. This study evaluates breath-hold (BH) motion stability and workflow impact using an in-bore surface...
Magnetic resonance (MR)–only radiotherapy planning requires accurate synthetic CT (sCT) generation from images acquired using standard clinical MRI simulation protocols. However, MRI acquisition protocols vary substantially across anatomical sites, and many e...
Lung cancer cases frequently involve multiple lesions, and treatment with a single isocenter can introduce geometric uncertainties, particularly due to inter-fraction motion. Online adaptive radiotherapy (ART) offers a strategy to mitigate these effects. This...
Therapy Physics