To develop an automated framework that determines the number and placement of isocenters and target margins for extracranial stereotactic ablative radiotherapy (SABR) in polymetastatic disease, and evaluate lung dose tradeoffs versus uniform margins.
Author profile
Jordan M. Slagowski, PhD
Department of Human Oncology, University of Wisconsin-Madison
To develop and validate a 3D deep learning autosegmentation model for prostate and OAR contouring on post-brachytherapy-catheter CT images for HDR prostate brachytherapy planning.
AAPM WGTG51 Report 374 emphasizes the importance of field barometer cross-calibration versus a reference barometer prior to reference dosimetry measurements. This work evaluates the validity of single-point calibration across altitudes and whether multi-point...
Catheter position uncertainty produces dosimetric error in HDR prostate brachytherapy, with reported displacements between planning and delivery of up to 5-7mm. Current inverse planning methods optimize dwell times for fixed catheter positions without account...
Focal dose escalation to the dominant intraprostatic lesion (GTV) improves biochemical control but is limited by urethral toxicity. 177Lu-PSMA radiopharmaceutical therapy (RPT) offers a targeted boost, yet its spatial heterogeneity in uptake leaves GTV sub-re...