To evaluate the delivery accuracy and treatment plan quality of the RefleXion X2 system with a developmental anchor point tracking delivery algorithm for large PET-avid targets, with specific emphasis on the treatment planning and performance improvements.
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Manoj Narayanan, PhD
RefleXion Medical
This work demonstrates the dosimetric performance of the developmental Anchor Point Tracking algorithm using phantom data acquired on the RefleXion X2 system with wide field-of-view PET detectors and software emulation of treatment planning and delivery.
The RefleXion X1 system requires activity concentration (AC) >5 kBq/mL for successful biology-guided radiotherapy (BgRT). We evaluated whether the extended field-of-view (FOV) PET detector in a can lower this AC threshold and expand treatment eligibility.
The next-generation PET-based SCINTIX® Biology-guided radiotherapy (BgRT) X2 platform incorporates a four-time PET widened field of view (WFOV) and an anchor-point-tracking delivery algorithm (currently in development). These advancements are intended to impr...