Manju Sharma, PhD

Radiopharmaceuticals, Theranostics, and Nuclear Medicine

Global advances in medical physics depend on interconnected research networks that facilitate mentoring, funding, collaboration, and long-term sustainability. Advancing cancer care worldwide requires a systematic, measurable, and globally interconnected resea...

This study presents a hybrid framework combining Vision Transformer (ViT) and handcrafted radiomic features for oropharyngeal carcinoma (OPC), to enhance multi-endpoint survival prediction.

Stereotactic radiosurgery (SRS) reirradiation for locally recurrent brain metastases (BM) utilizes rigid image registration (RIR) for cumulative dose estimation to balance dose escalation against the risk of adverse radiation effects such as radionecrosis. Th...

Open-source radiotherapy quality assurance (OSQA) tools are increasingly available and offer potential value in resource-constrained settings. However, clinical adoption remains limited by gaps in validation, standardization, and implementation guidance, rath...

Phase II and III clinical trials establish standards of care in radiation oncology; however, achieving equivalent clinical outcomes in routine practice depends on the reproducible implementation of trial protocols. We systematically evaluated whether publishe...

Therapy Physics

PEG dependence is widely considered a consequence of head and neck re-irradiation (HN re-RT), yet PEG persistence around treatment is frequently misinterpreted as durable swallowing toxicity. We introduce a time-anchored definition of persistent PEG dependenc...