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Author profile
Alessio Parisi, PhD
Mayo Clinic
A Clinical Dose Prescription System for Proton Radiotherapy Based on Microdosimetric Spectral Information
Clinical proton dose prescription uses a fixed relative biological effectiveness (RBE) factor of 1.1 despite preclinical and clinical evidence that RBE varies with dose, radiation quality and tissue radiosensitivity, particularly near the distal edge of treat...
Poster Program · Therapy Physics
Comparison of Two Novel Fully-Predictive Approaches to Compute NTCP Curves for Radiation-Induced Myelopathy In Rats Exposed to H, He, C, and O Ions
Toxicities to organs remain a critical limitation to dose escalation in radiotherapy. Ion radiotherapy reduces the absorbed dose to normal tissue but is characterized by a higher relative biological effectiveness (RBE). Existing clinically relevant methodolog...
Poster Program · Therapy Physics
Preliminary Monte Carlo Benchmarking of the First U.S. Carbon TPS: Range, Voxel-Wise Differences, and Microdosimetry
To present preliminary validation results for the first carbon treatment planning system (TPS) in the United States and to benchmark its GPU Monte Carlo dose engine using depth-resolved dose and microdosimetric metrics.
Poster Program · Therapy Physics