Histology-Based Microscale Human Spleen Model for Radiopharmaceutical Therapy Dosimetry
For radiopharmaceuticals emitting high linear energy transfer (LET) particles, such as alpha particles, the spleen can receive substantial localized doses due to its reticuloendothelial function. To capture dose heterogeneity, this study aims to develop three...
Poster Program · Radiopharmaceuticals, Theranostics, and Nuclear Medicine
Specific Absorbed Fractions and Radionuclide S Values for Human Spleen Microstructure for Radiopharmaceutical Dosimetry
Following radiopharmaceutical administration, absorbed doses can be estimated by coupling radionuclide S values with cumulated activity. For alpha-emitting radiopharmaceuticals, S values should be established at a microscale level to account for heterogeneous...
Poster Program · Radiopharmaceuticals, Theranostics, and Nuclear Medicine