Joshua Meyer, M.D.

Single-isocenter SBRT enables efficient treatment of multiple liver metastases but limits mitigation of rotational error. This study evaluates rotational uncertainty effects on target coverage in single-isocenter liver SBRT for patients with 5+ metastases.

Organ at risk dose limits as a function of varying fractionation scheme are conveniently given in the well-known “Timmerman tables”. Application of these limits in the re-treatment environment using the LQ approach (EQD2) can lead to overestimation of availab...