Author profile
University of Iowa
Dynamic collimation is emerging as a next-generation energy-specific collimating technology that can drastically improve the lateral and distal conformity of Pencil Beam Scanning (PBS) proton therapy. Current treatment delivery approaches rely on static step-...
GPUMCD, a GPU-accelerated Monte Carlo dose calculation algorithm, was recently released for clinical implementation in the Elekta One Treatment Planning System (v6.2.3, EOP) for c-arm Elekta linear accelerators (linac). The purpose of this work was to validat...
To experimentally quantify the mechanical delivery errors of a pre-clinical Dynamical Collimation System (DCS) prototype for intensity modulated proton therapy (IMPT) and evaluate the dosimetric impact of these errors to the target coverage and organ sparing.
Accurate small‑field dosimetry on MR‑linacs remains challenging due to magnetic‑field–induced dose perturbations and steep dose gradients. In this study, the performance of a newly developed unshielded silicon diode has been evaluated for use in small-field d...
Hyperpolarized Xenon imaging is a recent FDA-approved MRI technique that can measure physiological changes in ventilation, membrane uptake, and red blood cell transfer of gas throughout the lung. The scope of this work is to demonstrate the feasibility of int...
Accurate real-time tumor tracking is critical for MRI-guided radiotherapy, where geometric uncertainty can significantly increase dose to surrounding critical organs. Continuous cine-MRI enables motion-adaptive treatment. However, accurate tracking under larg...
Dose-optimized proton pencil beam scanning (PBS) treatments that are collimated using the Dynamic Collimation System (DCS) have greater dosimetric sparing of healthy tissue compared to uncollimated treatment plans, but differences in linear energy transfer (L...