Ryan C. O'Connell, PhD

To evaluate tumor oxygenation response to hyperbaric oxygen therapy using oxygen-enhanced MRI (OE-MRI) and assess whether elevated oxygen partial pressure can convert hypoxic, radiation-resistant tumor regions to a more radiosensitive state.

To evaluate the Oxygen Response Index (ORI) as a new oxygen-enhanced MRI (OE-MRI) metric for quantifying tumor radiation therapy efficacy that accounts for tissue oxygen response and tumor size, and to compare its sensitivity for detecting treatment response...