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New York Proton Center
To implement a full abdominal motion model that combines respiration with gastrointestinal (GI) motility and quantify its interplay impact in pencil-beam scanning (PBS) proton therapy.
Intensity-modulated proton therapy (IMPT) plan optimization is time-intensive due to its high dimensionality and the inherent non-convexity of clinical dosimetric constraints. Conventional algorithms like projected gradient descent (PGD) often require extensi...
To quantify the impact of gastrointestinal (GI) motility on pencil-beam scanning (PBS) proton therapy for abdominal cancers, and assess how fractionation and motion amplitude mitigate motility-induced interplay effects.