Noufal Manthala Padannayil, PhD

DynamicARC is a pencil beam scanning (PBS) proton therapy technique designed to improve delivery efficiency and plan quality. This study evaluated how energy layer spacing (ELS) affects target coverage, dose homogeneity, and organ-at-risk (OAR) sparing in lun...

To evaluate the feasibility of treating a large superficial skin (scalp) cancer target with a 3-field static IMPT technique and to assess the potential impact of elevated LET in high-dose regions.

We share our institutional experience upgrading Varian ARIA to v18.1/18. 2 in a multi-vendor radiation therapy environment, highlighting practical challenges, mitigations, and actionable lessons for centers planning similar upgrades.

To quantify the impact of a prostate motion model on target robustness under setup and range uncertainty, and to evaluate whether anatomical robust optimization improves robustness while maintaining nominal OAR constraint compliance.

To assess the feasibility of prostate stereotactic body radiation therapy (SBRT) in patients with unilateral and bilateral hip prostheses across multiple treatment platforms, focusing on image quality, planning feasibility, delivery characteristics, motion ma...

To develop and evaluate an in-house .NET/C# Eclipse Scripting API (ESAPI) solution with a dynamic universal graphical user interface (UGUI) to automate optimization-structure creation across disease sites and reduce treatment planning time.

Deep-learning (DL) auto-segmentation may improve efficiency in head-and-neck (HN) planning, but clinical use depends on how consistently experts judge contour acceptability and how performance varies by organ. We evaluated a DL-based auto-segmentation system...

To compare head-and-neck (HN) IMPT robustness using a conventional systematic setup uncertainty model versus a probabilistic random (interfractional) setup uncertainty model.