Radiotherapy has emerged as an effective noninvasive treatment for refractory ventricular tachycardia (VT). Given the high sensitivity of cardiac structures, proton therapy offers potential dosimetric advantages, but its robustness under cardiopulmonary motio...
Author profile
Xiaoying Fan
Department of Graduate, Shandong First Medical University, Shandong Academy of Medical Sciences
Severe radiation-induced lymphopenia (SRIL) is a detrimental prognostic factor in lung cancer. This study aimed to develop and validate normal tissue complication probability (NTCP) models for SRIL based on hematologic dose in patients receiving intensity-mod...
Spatially fractionated radiotherapy (SFRT) treats bulky tumors by creating heterogeneous dose distributions. Although both photon- and proton-based SFRT are accessible, various definitions of the peak-to-valley dose ratio (PVDR) may result in distinct dose di...
Hepatocellular carcinoma (HCC) treatment with intensity-modulated proton therapy (IMPT) is challenged by respiratory motion, necessitating 4D robust optimization. This study aimed to optimize the number of breathing phases required for 4D robust IMPT planning...
The Bragg peak of proton beam enables precise dose delivery and superior dose modulation in proton lattice radiotherapy (LRT), yet it remains susceptible to uncertainties. This study aims to investigate the impact of robust parameter settings and respiratory...