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Author profile
Nolan M. Esplen
Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Commissioning and Early Clinical Experience with a Preplan-Based MRI-Assisted Radiosurgery (MARS) HDR Prostate Brachytherapy Workflow
Preplanning is a standard practice for MRI-Assisted Radiosurgery (MARS) LDR prostate brachytherapy; however, HDR procedures often rely on generic needle patterns rather than individualized preplans. Implementing a patient-specific HDR preplan provides an oppo...
Poster Program · Therapy Physics
Comprehensive Characterization of Beam Current Transformers for the Performance Evaluation of Flash Linacs Producing Ultra-High Dose Rates for Flash Radiotherapy
The beam output of linacs producing ultra-high dose rates for FLASH radiotherapy (FLASH linacs) can exhibit significant and sometimes unpredictable variations in response to beam parameter adjustments, differing even among identical models. This study aims to...
Poster Program · Therapy Physics
Evaluation of Equivalent Toxicity and Associated Tumor Control for Broad-Beam and Ultra-High Dose Rate Spatially-Fractionated Radiotherapy on a Kilovoltage X-Ray Source
To establish a preclinical x-ray platform for delivering broad-beam (BB) and spatially-fractionated radiotherapy (SFRT) at conventional (CONV) and ultra-high dose rates (UHDR), and to determine the capacity for SFRT to maintain tumor control at doses elicitin...
Proffered Program · Therapy Physics
Dose‑Rate–Dependent Modulation of Radiolytic Hydroxyl Radical (•OH) Yield In Water Under Electron and Proton Flash Irradiation
FLASH radiotherapy (FLASH‑RT) employs ultra‑high dose rates (UHDR) that preferentially spare normal tissues relative to conventional dose‑rate radiotherapy (CONV‑RT) while maintaining tumor control, this is known as the FLASH effect. A proposed mechanistic ex...
Proffered Program · Therapy Physics
Development of a Mailable Pre-Clinical Flash Phantom for Remote Auditing of Ultra-High Dose Rate (FLASH) Radiotherapy
To design and validate a phantom capable of remote temporal and point dose rate assessment for electron and proton FLASH beams, with integrated spatial information to enable full end to end verification.
Proffered Program · Therapy Physics