Jingjie Yu

In multi-target Gamma Knife (GK) radiosurgery, the clinical default plan typically sequences shots based on geometric efficiency to minimize treatment duration. However, this approach ignores the time-dependent biological effects of sublethal damage repair. T...

Current Gamma Knife (GK) planning typically decouples isocenter placement (heuristic-based) from sector duration optimization (SDO). This separation often leads to suboptimal plan quality and prolonged beam-on time (BOT). We propose an Integrated Isocenter an...