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New York Proton Center
To implement a full abdominal motion model that combines respiration with gastrointestinal (GI) motility and quantify its interplay impact in pencil-beam scanning (PBS) proton therapy.
Proton LATTICE radiotherapy (LRT), a spatially fractionated radiotherapy (SFRT), delivers high dose to intratumoral vertices while maintaining low valley dose. Single-field optimization (SFO) is robust in preserving peak-to-valley patterns but may increase en...
To systematically evaluate if optimized spot-delivery patterns in pencil-beam scanning can reach FLASH-compatible dose rates (>40Gy/s) at clinically relevant fractions of 4Gy and to identify key machine and planning parameters for whole-brain irradiation (WBI...
To quantify the impact of gastrointestinal (GI) motility on pencil-beam scanning (PBS) proton therapy for abdominal cancers, and assess how fractionation and motion amplitude mitigate motility-induced interplay effects.