Author profile
Department of Radiation Oncology Physics and Technology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences
Contrast-enhanced CT (CECT) is routinely used in radiotherapy planning to improve visualization of tumors, lymph nodes, and vascular anatomy for accurate target delineation. However, contrast administration is contraindicated in a subset of patients (e.g., io...
This study evaluated the impact of interfractional rectal state changes on plan robustness in cervical cancer intensity-modulated proton therapy (IMPT) and established a robust optimization strategy incorporating multiple rectal conditions.
Radiotherapy has emerged as an effective noninvasive treatment for refractory ventricular tachycardia (VT). Given the high sensitivity of cardiac structures, proton therapy offers potential dosimetric advantages, but its robustness under cardiopulmonary motio...
Severe radiation-induced lymphopenia (SRIL) is a detrimental prognostic factor in lung cancer. This study aimed to develop and validate normal tissue complication probability (NTCP) models for SRIL based on hematologic dose in patients receiving intensity-mod...
Spatially fractionated radiotherapy (SFRT) treats bulky tumors by creating heterogeneous dose distributions. Although both photon- and proton-based SFRT are accessible, various definitions of the peak-to-valley dose ratio (PVDR) may result in distinct dose di...
Concurrent chemoradiotherapy combined with image-guided brachytherapy is the standard for locally advanced cervical cancer, yet failures persist due to heterogeneous radioresistant sub-volumes. While Dose Painting by Numbers (DPbN) enables voxel-level modulat...
To develop and validate a robust CT-radiomics framework using feature-level multicenter distribution adaptation (MDA) to differentiate pulmonary tuberculosis (TB) from fungal pneumonia (FP), explicitly addressing the challenge of inter-scanner variability and...
Hepatocellular carcinoma (HCC) treatment with intensity-modulated proton therapy (IMPT) is challenged by respiratory motion, necessitating 4D robust optimization. This study aimed to optimize the number of breathing phases required for 4D robust IMPT planning...
This study systematically evaluated the robustness of radiomics features derived from photon-counting detector CT (PCD-CT) and three dual-energy CT (DECT) platforms under different reconstruction strategies and scanning conditions using chest tumor phantoms.
Inter-fractional anatomical changes in lung SBRT raise concerns about dosimetric accuracy and potential target under-dosage. Adaptive radiotherapy (ART) is a proposed strategy to correct these variations. This study aims to quantify the dosimetric degradation...
The Bragg peak of proton beam enables precise dose delivery and superior dose modulation in proton lattice radiotherapy (LRT), yet it remains susceptible to uncertainties. This study aims to investigate the impact of robust parameter settings and respiratory...