Author profile
National Cancer Centre Singapore
Dose Driven Continous Scanning proton therapy offers reduced beam delivery time compared to discrete spot scanning but requires accurate characterization of temporal beam parameters for precise dose calculation. This study quantified rise time (trise) and pla...
To develop and validate a novel hybrid framework for five-material decomposition (water, fat, bone, iodine, and lung) using three-energy Photon-Counting CT (PCCT). By integrating multi-energy spectral analysis with density-constrained dynamic basis selection,...
Stopping power ratio (SPR) estimation from dual-energy CT (DECT) may improve proton range accuracy by eliminating conventional HU calibration uncertainties. Commercial proprietary algorithms, such as DirectSPR, necessitate independent verification methods dur...
To develop normal tissue complication probability (NTCP) models for Grade 3 (G3) radiation dermatitis in nasopharyngeal carcinoma (NPC) patients treated with photon and proton therapy, and to evaluate their generalizability across the two treatment modalities.