Muskan Lather

To refine the photochemical dose–response relationship for single-fraction Photofrin-mediated PDT by relating modeled reacted singlet oxygen dose to long-term tumor control and by using multispectral singlet oxygen luminescence detection (MSOLD) as an indepen...

Singlet oxygen (SO) is the primary cytotoxic agent in photodynamic therapy (PDT); however, real-time measurement of SO during treatment remains challenging. The purpose of this study is to investigate the dependence of SO signal on tissue oxygenation and trea...

Time-resolved singlet oxygen luminescence detection (TSOLD) enables direct measurement of singlet oxygen generation during photodynamic therapy (PDT), while multispectral SOLD (MSOLD) and singlet oxygen explicit dosimetry (SOED) provide complementary cumulati...