Author profile
Department of Radiation Oncology, Brigham and Women’s Hospital, Dana-Farber Cancer Institute, Harvard Medical School
Cone beam CTs at typical kV energies exhibit metal artifacts in IGRT patients with metal prosthetics. MV-CBCT, available on some linacs, reduces artifacts at the expense of soft tissue contrast-to-noise (CNR). As a remedy, we propose an AI network to convert...
To clinically implement and evaluate an MRI-only treatment planning (MRTP) workflow for interstitial high-dose-rate (HDR) brachytherapy in gynecologic cancers. In contrast to the conventional CT/MRI-based planning (CTP) approach, MRTP eliminates CT imaging, t...
During lung SBRT, tumor motion is managed using 4DCT-based ITV expansion, respiratory or external gating, or breath-hold techniques, each with limitations. Existing real-time tracking methods require implanted fiducials or additional imaging dose. A non-invas...
To evaluate the dosimetric accuracy of plans calculated on the Varian TrueBeam HyperSight cone beam CT (CTHS) imager upgrade compared to current fan beam simulation CT (CTSim) solutions towards online adaptive radiotherapy.
Conventional dual-energy material decomposition methods suffer from significant noise amplification, which limits their clinical utility for tasks such as intra-fraction markerless tumor tracking. This study introduces PRISM, an open-source Julia framework sp...
Dual-layer imagers (DLIs) enable simultaneous acquisition of low- and high-energy images in a single exposure, offering detector-based spectral imaging capability for the on-board kV imaging systems of conventional linear accelerators towards avoiding motion...
To evaluate the correlation between lung tumor and pulmonary vessel motion under MR-guided radiotherapy and to inform surrogate tracking feature selection when direct tumor tracking is challenging.
Spectral imaging confers several benefits such as material decomposition, increased soft tissue contrast, and metal artifact reduction. Novel methods currently under evaluation for adoption to linac onboard imaging include a kV dual-layer imager investigated...
Therapy Physics